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Risk Factors Associated with Colorectal Cancer in a Subset of Patients with Mutations in MLH1 and MSH2 in Taiwan Fulfilling the Amsterdam II Criteria for Lynch Syndrome

BACKGROUND AND AIM: Lynch syndrome, caused by germline mutations in mismatch repair genes, is a predisposing factor for colorectal cancer (CRC). This retrospective cohort study investigated the risk factors associated with the development of CRC in patients with MLH1 and MSH2 germline mutations. MET...

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Detalles Bibliográficos
Autores principales:	Kamiza, Abram Bunya, Hsieh, Ling-Ling, Tang, Reiping, Chien, Huei-Tzu, Lai, Chih-Hsiung, Chiu, Li-Ling, Lo, Tsai-Ping, Hung, Kuan-Yi, Wang, Chun-Yi, You, Jeng-Fu, Hsiung, Chao A., Yeh, Chih-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460082/ https://www.ncbi.nlm.nih.gov/pubmed/26053027 http://dx.doi.org/10.1371/journal.pone.0130018

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