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Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients
To evaluate the beneficial and adverse effects of breviscapine injection in combination with Western medicine on the treatment of patients with angina pectoris. The Cochrane Central Register of Controlled Trials, Medline, Science Citation Index, EMBASE, the China National Knowledge Infrastructure, t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460136/ https://www.ncbi.nlm.nih.gov/pubmed/26052709 http://dx.doi.org/10.1371/journal.pone.0129969 |
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author | Wang, Chuan Li, Yafeng Gao, Shoucui Cheng, Daxin Zhao, Sihai Liu, Enqi |
author_facet | Wang, Chuan Li, Yafeng Gao, Shoucui Cheng, Daxin Zhao, Sihai Liu, Enqi |
author_sort | Wang, Chuan |
collection | PubMed |
description | To evaluate the beneficial and adverse effects of breviscapine injection in combination with Western medicine on the treatment of patients with angina pectoris. The Cochrane Central Register of Controlled Trials, Medline, Science Citation Index, EMBASE, the China National Knowledge Infrastructure, the Wanfang Database, the Chongqing VIP Information Database and the China Biomedical Database were searched to identify randomized clinical trials (RCTs) that evaluated the effects of Western medicine compared to breviscapine injection plus Western medicine on angina pectoris patients. The included studies were analyzed using RevMan 5.1.0 software. The literature search yielded 460 studies, wherein 16 studies matched the selection criteria. The results showed that combined therapy using Breviscapine plus Western medicine was superior to Western medicine alone for improving angina pectoris symptoms (OR =3.77, 95% Cl: 2.76~5.15) and also resulted in increased electrocardiogram (ECG) improvement (OR=2.77, 95% Cl: 2.16~3.53). The current evidence suggests that Breviscapine plus Western medicine achieved a superior therapeutic effect compared to Western medicine alone. |
format | Online Article Text |
id | pubmed-4460136 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-44601362015-06-16 Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients Wang, Chuan Li, Yafeng Gao, Shoucui Cheng, Daxin Zhao, Sihai Liu, Enqi PLoS One Research Article To evaluate the beneficial and adverse effects of breviscapine injection in combination with Western medicine on the treatment of patients with angina pectoris. The Cochrane Central Register of Controlled Trials, Medline, Science Citation Index, EMBASE, the China National Knowledge Infrastructure, the Wanfang Database, the Chongqing VIP Information Database and the China Biomedical Database were searched to identify randomized clinical trials (RCTs) that evaluated the effects of Western medicine compared to breviscapine injection plus Western medicine on angina pectoris patients. The included studies were analyzed using RevMan 5.1.0 software. The literature search yielded 460 studies, wherein 16 studies matched the selection criteria. The results showed that combined therapy using Breviscapine plus Western medicine was superior to Western medicine alone for improving angina pectoris symptoms (OR =3.77, 95% Cl: 2.76~5.15) and also resulted in increased electrocardiogram (ECG) improvement (OR=2.77, 95% Cl: 2.16~3.53). The current evidence suggests that Breviscapine plus Western medicine achieved a superior therapeutic effect compared to Western medicine alone. Public Library of Science 2015-06-08 /pmc/articles/PMC4460136/ /pubmed/26052709 http://dx.doi.org/10.1371/journal.pone.0129969 Text en © 2015 Wang et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Wang, Chuan Li, Yafeng Gao, Shoucui Cheng, Daxin Zhao, Sihai Liu, Enqi Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients |
title | Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients |
title_full | Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients |
title_fullStr | Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients |
title_full_unstemmed | Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients |
title_short | Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients |
title_sort | breviscapine injection improves the therapeutic effect of western medicine on angina pectoris patients |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460136/ https://www.ncbi.nlm.nih.gov/pubmed/26052709 http://dx.doi.org/10.1371/journal.pone.0129969 |
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