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Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients

To evaluate the beneficial and adverse effects of breviscapine injection in combination with Western medicine on the treatment of patients with angina pectoris. The Cochrane Central Register of Controlled Trials, Medline, Science Citation Index, EMBASE, the China National Knowledge Infrastructure, t...

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Autores principales: Wang, Chuan, Li, Yafeng, Gao, Shoucui, Cheng, Daxin, Zhao, Sihai, Liu, Enqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460136/
https://www.ncbi.nlm.nih.gov/pubmed/26052709
http://dx.doi.org/10.1371/journal.pone.0129969
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author Wang, Chuan
Li, Yafeng
Gao, Shoucui
Cheng, Daxin
Zhao, Sihai
Liu, Enqi
author_facet Wang, Chuan
Li, Yafeng
Gao, Shoucui
Cheng, Daxin
Zhao, Sihai
Liu, Enqi
author_sort Wang, Chuan
collection PubMed
description To evaluate the beneficial and adverse effects of breviscapine injection in combination with Western medicine on the treatment of patients with angina pectoris. The Cochrane Central Register of Controlled Trials, Medline, Science Citation Index, EMBASE, the China National Knowledge Infrastructure, the Wanfang Database, the Chongqing VIP Information Database and the China Biomedical Database were searched to identify randomized clinical trials (RCTs) that evaluated the effects of Western medicine compared to breviscapine injection plus Western medicine on angina pectoris patients. The included studies were analyzed using RevMan 5.1.0 software. The literature search yielded 460 studies, wherein 16 studies matched the selection criteria. The results showed that combined therapy using Breviscapine plus Western medicine was superior to Western medicine alone for improving angina pectoris symptoms (OR =3.77, 95% Cl: 2.76~5.15) and also resulted in increased electrocardiogram (ECG) improvement (OR=2.77, 95% Cl: 2.16~3.53). The current evidence suggests that Breviscapine plus Western medicine achieved a superior therapeutic effect compared to Western medicine alone.
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spelling pubmed-44601362015-06-16 Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients Wang, Chuan Li, Yafeng Gao, Shoucui Cheng, Daxin Zhao, Sihai Liu, Enqi PLoS One Research Article To evaluate the beneficial and adverse effects of breviscapine injection in combination with Western medicine on the treatment of patients with angina pectoris. The Cochrane Central Register of Controlled Trials, Medline, Science Citation Index, EMBASE, the China National Knowledge Infrastructure, the Wanfang Database, the Chongqing VIP Information Database and the China Biomedical Database were searched to identify randomized clinical trials (RCTs) that evaluated the effects of Western medicine compared to breviscapine injection plus Western medicine on angina pectoris patients. The included studies were analyzed using RevMan 5.1.0 software. The literature search yielded 460 studies, wherein 16 studies matched the selection criteria. The results showed that combined therapy using Breviscapine plus Western medicine was superior to Western medicine alone for improving angina pectoris symptoms (OR =3.77, 95% Cl: 2.76~5.15) and also resulted in increased electrocardiogram (ECG) improvement (OR=2.77, 95% Cl: 2.16~3.53). The current evidence suggests that Breviscapine plus Western medicine achieved a superior therapeutic effect compared to Western medicine alone. Public Library of Science 2015-06-08 /pmc/articles/PMC4460136/ /pubmed/26052709 http://dx.doi.org/10.1371/journal.pone.0129969 Text en © 2015 Wang et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Wang, Chuan
Li, Yafeng
Gao, Shoucui
Cheng, Daxin
Zhao, Sihai
Liu, Enqi
Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients
title Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients
title_full Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients
title_fullStr Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients
title_full_unstemmed Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients
title_short Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients
title_sort breviscapine injection improves the therapeutic effect of western medicine on angina pectoris patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460136/
https://www.ncbi.nlm.nih.gov/pubmed/26052709
http://dx.doi.org/10.1371/journal.pone.0129969
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