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Live imaging and modeling of inner nuclear membrane targeting reveals its molecular requirements in mammalian cells

Targeting of inner nuclear membrane (INM) proteins is essential for nuclear architecture and function, yet its mechanism remains poorly understood. Here, we established a new reporter that allows real-time imaging of membrane protein transport from the ER to the INM using Lamin B receptor and Lap2β...

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Detalles Bibliográficos
Autores principales:	Boni, Andrea, Politi, Antonio Z., Strnad, Petr, Xiang, Wanqing, Hossain, M. Julius, Ellenberg, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460149/ https://www.ncbi.nlm.nih.gov/pubmed/26056140 http://dx.doi.org/10.1083/jcb.201409133

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