The mitochondrial Na(+)/Ca(2+) exchanger may reduce high glucose-induced oxidative stress and nucleotide-binding oligomerization domain receptor 3 inflammasome activation in endothelial cells

BACKGROUND: The mitochondrial Na(+)/Ca(2+) exchanger, NCLX, plays an important role in the balance between Ca(2+) influx and efflux across the mitochondrial inner membrane in endothelial cells. Mitochondrial metabolism is likely to be affected by the activity of NCLX because Ca(2+) activates several...

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Detalles Bibliográficos
Autores principales: Zu, Yuan, Wan, Li-Juan, Cui, Shao-Yuan, Gong, Yan-Ping, Li, Chun-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460171/
https://www.ncbi.nlm.nih.gov/pubmed/26089852
http://dx.doi.org/10.11909/j.issn.1671-5411.2015.03.003

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