A Case of Immunoglobulin G4-Related Disease with Extensive Multiorgan Involvements

We report a case of IgG4-related disease (IgG4-RD) with multiple ten-organ involvement. This case showed many clinical findings, such as bilateral swelling of salivary and lacrimal glands, autoimmune pancreatitis, interstitial nephritis, retroperitoneal fibrosis, periaortitis, systemic swelling of l...

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Autores principales: Higashioka, Kazuhiko, Yoshida, Kenji, Oryoji, Kensuke, Kamada, Kazuo, Mizuki, Shinichi, Tsukamoto, Hiroshi, Yokota, Eisuke, Akashi, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460202/
https://www.ncbi.nlm.nih.gov/pubmed/26101684
http://dx.doi.org/10.1155/2015/392893
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author Higashioka, Kazuhiko
Yoshida, Kenji
Oryoji, Kensuke
Kamada, Kazuo
Mizuki, Shinichi
Tsukamoto, Hiroshi
Yokota, Eisuke
Akashi, Koichi
author_facet Higashioka, Kazuhiko
Yoshida, Kenji
Oryoji, Kensuke
Kamada, Kazuo
Mizuki, Shinichi
Tsukamoto, Hiroshi
Yokota, Eisuke
Akashi, Koichi
author_sort Higashioka, Kazuhiko
collection PubMed
description We report a case of IgG4-related disease (IgG4-RD) with multiple ten-organ involvement. This case showed many clinical findings, such as bilateral swelling of salivary and lacrimal glands, autoimmune pancreatitis, interstitial nephritis, retroperitoneal fibrosis, periaortitis, systemic swelling of lymph nodes, pulmonary lesions, splenomegaly, and jejunal lesions. He was suspected as having SLE or malignant lymphoma but diagnosed as having IgG4-RD by the elevated serum IgG4 level and histological findings from kidney and lymph node. We report a case of IgG4-RD with multiple ten-organ involvement that was successfully treated with prednisolone therapy.
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spelling pubmed-44602022015-06-22 A Case of Immunoglobulin G4-Related Disease with Extensive Multiorgan Involvements Higashioka, Kazuhiko Yoshida, Kenji Oryoji, Kensuke Kamada, Kazuo Mizuki, Shinichi Tsukamoto, Hiroshi Yokota, Eisuke Akashi, Koichi Case Rep Rheumatol Case Report We report a case of IgG4-related disease (IgG4-RD) with multiple ten-organ involvement. This case showed many clinical findings, such as bilateral swelling of salivary and lacrimal glands, autoimmune pancreatitis, interstitial nephritis, retroperitoneal fibrosis, periaortitis, systemic swelling of lymph nodes, pulmonary lesions, splenomegaly, and jejunal lesions. He was suspected as having SLE or malignant lymphoma but diagnosed as having IgG4-RD by the elevated serum IgG4 level and histological findings from kidney and lymph node. We report a case of IgG4-RD with multiple ten-organ involvement that was successfully treated with prednisolone therapy. Hindawi Publishing Corporation 2015 2015-05-26 /pmc/articles/PMC4460202/ /pubmed/26101684 http://dx.doi.org/10.1155/2015/392893 Text en Copyright © 2015 Kazuhiko Higashioka et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Higashioka, Kazuhiko
Yoshida, Kenji
Oryoji, Kensuke
Kamada, Kazuo
Mizuki, Shinichi
Tsukamoto, Hiroshi
Yokota, Eisuke
Akashi, Koichi
A Case of Immunoglobulin G4-Related Disease with Extensive Multiorgan Involvements
title A Case of Immunoglobulin G4-Related Disease with Extensive Multiorgan Involvements
title_full A Case of Immunoglobulin G4-Related Disease with Extensive Multiorgan Involvements
title_fullStr A Case of Immunoglobulin G4-Related Disease with Extensive Multiorgan Involvements
title_full_unstemmed A Case of Immunoglobulin G4-Related Disease with Extensive Multiorgan Involvements
title_short A Case of Immunoglobulin G4-Related Disease with Extensive Multiorgan Involvements
title_sort case of immunoglobulin g4-related disease with extensive multiorgan involvements
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460202/
https://www.ncbi.nlm.nih.gov/pubmed/26101684
http://dx.doi.org/10.1155/2015/392893
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