Modulation of Acid Sphingomyelinase in Melanoma Reprogrammes the Tumour Immune Microenvironment

The inflammatory microenvironment induces tumours to acquire an aggressive and immunosuppressive behaviour. Since acid sphingomyelinase (A-SMase) downregulation in melanoma was shown to determine a malignant phenotype, we aimed here to elucidate the role of A-SMase in the regulation of tumour immuno...

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Detalles Bibliográficos
Autores principales: Assi, Emma, Cervia, Davide, Bizzozero, Laura, Capobianco, Annalisa, Pambianco, Sarah, Morisi, Federica, De Palma, Clara, Moscheni, Claudia, Pellegrino, Paolo, Clementi, Emilio, Perrotta, Cristiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460251/
https://www.ncbi.nlm.nih.gov/pubmed/26101462
http://dx.doi.org/10.1155/2015/370482

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