(123)I-Metaiodobenzylguanidine Myocardial Scintigraphy in Lewy Body-Related Disorders: A Literature Review

Lewy body-related disorders are characterized by the presence of Lewy bodies and Lewy neurites, which have abnormal aggregations of α-synuclein in the nigral and extranigral areas, including in the heart. (123)I-metaiodobenzylguanidine (MIBG) scintigraphy is a well-known tool to evaluate cardiac sym...

Descripción completa

Detalles Bibliográficos
Autores principales: Chung, Eun Joo, Kim, Sang Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Movement Disorders Society 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460541/
https://www.ncbi.nlm.nih.gov/pubmed/26090077
http://dx.doi.org/10.14802/jmd.15015
_version_ 1782375387266809856
author Chung, Eun Joo
Kim, Sang Jin
author_facet Chung, Eun Joo
Kim, Sang Jin
author_sort Chung, Eun Joo
collection PubMed
description Lewy body-related disorders are characterized by the presence of Lewy bodies and Lewy neurites, which have abnormal aggregations of α-synuclein in the nigral and extranigral areas, including in the heart. (123)I-metaiodobenzylguanidine (MIBG) scintigraphy is a well-known tool to evaluate cardiac sympathetic denervation in the Lewy body-related disorders. MIBG scintigraphy showed low uptake of MIBG in the Lewy body-related disorders, including Parkinson’s disease, dementia with Lewy bodies, pure autonomic failure and rapid eye movement sleep behavior disorder. This review summarizes previous results on the diagnostic applications of MIBG scintigraphy in Lewy body-related disorders.
format Online
Article
Text
id pubmed-4460541
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher The Korean Movement Disorders Society
record_format MEDLINE/PubMed
spelling pubmed-44605412015-06-18 (123)I-Metaiodobenzylguanidine Myocardial Scintigraphy in Lewy Body-Related Disorders: A Literature Review Chung, Eun Joo Kim, Sang Jin J Mov Disord Review Article Lewy body-related disorders are characterized by the presence of Lewy bodies and Lewy neurites, which have abnormal aggregations of α-synuclein in the nigral and extranigral areas, including in the heart. (123)I-metaiodobenzylguanidine (MIBG) scintigraphy is a well-known tool to evaluate cardiac sympathetic denervation in the Lewy body-related disorders. MIBG scintigraphy showed low uptake of MIBG in the Lewy body-related disorders, including Parkinson’s disease, dementia with Lewy bodies, pure autonomic failure and rapid eye movement sleep behavior disorder. This review summarizes previous results on the diagnostic applications of MIBG scintigraphy in Lewy body-related disorders. The Korean Movement Disorders Society 2015-05 2015-05-31 /pmc/articles/PMC4460541/ /pubmed/26090077 http://dx.doi.org/10.14802/jmd.15015 Text en Copyright © 2015 The Korean Movement Disorder Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Chung, Eun Joo
Kim, Sang Jin
(123)I-Metaiodobenzylguanidine Myocardial Scintigraphy in Lewy Body-Related Disorders: A Literature Review
title (123)I-Metaiodobenzylguanidine Myocardial Scintigraphy in Lewy Body-Related Disorders: A Literature Review
title_full (123)I-Metaiodobenzylguanidine Myocardial Scintigraphy in Lewy Body-Related Disorders: A Literature Review
title_fullStr (123)I-Metaiodobenzylguanidine Myocardial Scintigraphy in Lewy Body-Related Disorders: A Literature Review
title_full_unstemmed (123)I-Metaiodobenzylguanidine Myocardial Scintigraphy in Lewy Body-Related Disorders: A Literature Review
title_short (123)I-Metaiodobenzylguanidine Myocardial Scintigraphy in Lewy Body-Related Disorders: A Literature Review
title_sort (123)i-metaiodobenzylguanidine myocardial scintigraphy in lewy body-related disorders: a literature review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460541/
https://www.ncbi.nlm.nih.gov/pubmed/26090077
http://dx.doi.org/10.14802/jmd.15015
work_keys_str_mv AT chungeunjoo 123imetaiodobenzylguanidinemyocardialscintigraphyinlewybodyrelateddisordersaliteraturereview
AT kimsangjin 123imetaiodobenzylguanidinemyocardialscintigraphyinlewybodyrelateddisordersaliteraturereview

Ejemplares similares