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Inferring drug-disease associations based on known protein complexes
Inferring drug-disease associations is critical in unveiling disease mechanisms, as well as discovering novel functions of available drugs, or drug repositioning. Previous work is primarily based on drug-gene-disease relationship, which throws away many important information since genes execute thei...
Autores principales: | Yu, Liang, Huang, Jianbin, Ma, Zhixin, Zhang, Jing, Zou, Yapeng, Gao, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460611/ https://www.ncbi.nlm.nih.gov/pubmed/26044949 http://dx.doi.org/10.1186/1755-8794-8-S2-S2 |
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