High-level expression, purification, and enzymatic characterization of truncated human plasminogen (Lys531-Asn791) in the methylotrophic yeast Pichia pastoris

BACKGROUND: Plasmin is a serine protease that plays a critical role in fibrinolysis, which is a process that prevents blood clots from growing and becoming problematic. Recombinant human microplasminogen (rhμPlg) is a derivative of plasmin that solely consists of the catalytic domain of human plasmi...

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Detalles Bibliográficos
Autores principales: Liu, Rongzeng, Zhao, Bing, Zhang, Yanling, Gu, Junxiang, Yu, Mingrong, Song, Houyan, Yu, Min, Mo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460660/
https://www.ncbi.nlm.nih.gov/pubmed/26054637
http://dx.doi.org/10.1186/s12896-015-0179-z

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