Integrative epigenomic and genomic filtering for methylation markers in hepatocellular carcinomas

BACKGROUND: Epigenome-wide studies in hepatocellular carcinoma (HCC) have identified numerous genes with aberrant DNA methylation. However, methods for triaging functional candidate genes as useful biomarkers for epidemiological study have not yet been developed. METHODS: We conducted targeted next-...

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Detalles Bibliográficos
Autores principales: Shen, Jing, LeFave, Clare, Sirosh, Iryna, Siegel, Abby B., Tycko, Benjamin, Santella, Regina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460673/
https://www.ncbi.nlm.nih.gov/pubmed/26059414
http://dx.doi.org/10.1186/s12920-015-0105-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460673/
https://www.ncbi.nlm.nih.gov/pubmed/26059414
http://dx.doi.org/10.1186/s12920-015-0105-1

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