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Integrative epigenomic and genomic filtering for methylation markers in hepatocellular carcinomas
BACKGROUND: Epigenome-wide studies in hepatocellular carcinoma (HCC) have identified numerous genes with aberrant DNA methylation. However, methods for triaging functional candidate genes as useful biomarkers for epidemiological study have not yet been developed. METHODS: We conducted targeted next-...
Autores principales: | Shen, Jing, LeFave, Clare, Sirosh, Iryna, Siegel, Abby B., Tycko, Benjamin, Santella, Regina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460673/ https://www.ncbi.nlm.nih.gov/pubmed/26059414 http://dx.doi.org/10.1186/s12920-015-0105-1 |
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