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Comparative proteomics of cerebrospinal fluid reveals a predictive model for differential diagnosis of pneumococcal, meningococcal, and enteroviral meningitis, and novel putative therapeutic targets

BACKGROUND: Meningitis is the inflammation of the meninges in response to infection or chemical agents. While aseptic meningitis, most frequently caused by enteroviruses, is usually benign with a self-limiting course, bacterial meningitis remains associated with high morbidity and mortality rates, d...

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Detalles Bibliográficos
Autores principales: Cordeiro, Ana Paula, Pereira, Rosiane Aparecida Silva, Chapeaurouge, Alex, Coimbra, Clarice Semião, Perales, Jonas, Oliveira, Guilherme, Candiani, Talitah Michel Sanchez, Coimbra, Roney Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460676/
https://www.ncbi.nlm.nih.gov/pubmed/26040285
http://dx.doi.org/10.1186/1471-2164-16-S5-S11