Natural selection on HFE in Asian populations contributes to enhanced non-heme iron absorption

BACKGROUND: HFE, a major regulator of iron (Fe) homeostasis, has been suggested to be under positive selection in both European and Asian populations. While the genetic variant under selection in Europeans (a non-synonymous mutation, C282Y) has been relatively well-studied, the adaptive variant in A...

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Detalles Bibliográficos
Autores principales: Ye, Kaixiong, Cao, Chang, Lin, Xu, O’Brien, Kimberly O, Gu, Zhenglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460683/
https://www.ncbi.nlm.nih.gov/pubmed/26054392
http://dx.doi.org/10.1186/s12863-015-0223-y

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