Mixed response and time-to-event endpoints for multistage single-arm phase II design

BACKGROUND: The objective of phase II cancer clinical trials is to determine if a treatment has sufficient activity to warrant further study. The efficiency of a conventional phase II trial design has been the object of considerable debate, particularly when the study regimen is characteristically c...

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Detalles Bibliográficos
Autores principales: Lai, Xin, Zee, Benny Chung-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460691/
https://www.ncbi.nlm.nih.gov/pubmed/26037094
http://dx.doi.org/10.1186/s13063-015-0743-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460691/
https://www.ncbi.nlm.nih.gov/pubmed/26037094
http://dx.doi.org/10.1186/s13063-015-0743-9

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