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Single-Cell Phenotypic Characterization of Human Pituitary GHomas and Non-Functioning Adenomas Based on Hormone Content and Calcium Responses to Hypothalamic Releasing Hormones
Human pituitary tumors are generally benign adenomas causing considerable morbidity due to excess hormone secretion, hypopituitarism, and other tumor mass effects. Pituitary tumors are highly heterogeneous and difficult to type, often containing mixed cell phenotypes. We have used calcium imaging fo...
Autores principales: | Senovilla, Laura, Núñez, Lucía, de Campos, José María, de Luis, Daniel A., Romero, Enrique, García-Sancho, Javier, Villalobos, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460876/ https://www.ncbi.nlm.nih.gov/pubmed/26106585 http://dx.doi.org/10.3389/fonc.2015.00124 |
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