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A 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatment

BACKGROUND: Radiation resistance presents a challenge to the effective treatment of cancer. If therapeutic compounds were capable of resensitizing resistant tumours then a concurrent chemo-radiation treatment could be used to overcome radiation resistance. METHODS: We have developed a phenotypic ass...

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Detalles Bibliográficos
Autores principales: Anastasov, Nataša, Höfig, Ines, Radulović, Vanja, Ströbel, Simon, Salomon, Michael, Lichtenberg, Jan, Rothenaigner, Ina, Hadian, Kamyar, Kelm, Jens M., Thirion, Christian, Atkinson, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460881/
https://www.ncbi.nlm.nih.gov/pubmed/26059545
http://dx.doi.org/10.1186/s12885-015-1481-9