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Inferring regulatory element landscapes and transcription factor networks from cancer methylomes

Recent studies indicate that DNA methylation can be used to identify transcriptional enhancers, but no systematic approach has been developed for genome-wide identification and analysis of enhancers based on DNA methylation. We describe ELMER (Enhancer Linking by Methylation/Expression Relationships...

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Detalles Bibliográficos
Autores principales:	Yao, Lijing, Shen, Hui, Laird, Peter W, Farnham, Peggy J, Berman, Benjamin P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460959/ https://www.ncbi.nlm.nih.gov/pubmed/25994056 http://dx.doi.org/10.1186/s13059-015-0668-3

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