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Progressive age-associated activation of JNK associates with conduction disruption in the aged atrium
Connexin43 (Cx43) is critical for maintaining electrical conduction across atrial muscle. During progressive ageing atrial conduction slows associating with increasing susceptibility to arrhythmias. Changes in Cx43 protein expression, or its phosphorylation status, can instigate changes in the condu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Science Ireland
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461009/ https://www.ncbi.nlm.nih.gov/pubmed/25956603 http://dx.doi.org/10.1016/j.mad.2015.05.001 |