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XPD Functions as a Tumor Suppressor and Dysregulates Autophagy in Cultured HepG2 Cells

BACKGROUND: Recent clinical studies have linked polymorphisms in the xeroderma pigmentosum group D (XPD) gene, a key repair gene involved in nucleotide excision repair, to increased risk of hepatocellular carcinoma (HCC). However, the cellular effects of XPD expression in cultured HCC cells remain l...

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Detalles Bibliográficos
Autores principales: Zheng, Jian-feng, Li, Lin-lin, Lu, Juan, Yan, Kun, Guo, Wu-hua, Zhang, Ji-xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461047/
https://www.ncbi.nlm.nih.gov/pubmed/26031757
http://dx.doi.org/10.12659/MSM.894303

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