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TRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 Polymerase

Polymerase basic protein 1 (PB1) is the catalytic core of the influenza A virus (IAV) RNA polymerase complex essential for viral transcription and replication. Understanding the intrinsic mechanisms which block PB1 function could stimulate development of new anti-influenza therapeutics. Affinity pur...

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Detalles Bibliográficos
Autores principales:	Fu, Bishi, Wang, Lingyan, Ding, Hao, Schwamborn, Jens C., Li, Shitao, Dorf, Martin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461266/ https://www.ncbi.nlm.nih.gov/pubmed/26057645 http://dx.doi.org/10.1371/journal.ppat.1004960

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