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Mechanisms of Hypoxic Up-Regulation of Versican Gene Expression in Macrophages
Hypoxia is a hallmark of many pathological tissues. Macrophages accumulate in hypoxic sites and up-regulate a range of hypoxia-inducible genes. The matrix proteoglycan versican has been identified as one such gene, but the mechanisms responsible for hypoxic induction are not fully characterised. Her...
Autores principales: | Sotoodehnejadnematalahi, Fattah, Staples, Karl J., Chrysanthou, Elvina, Pearson, Helen, Ziegler-Heitbrock, Loems, Burke, Bernard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461269/ https://www.ncbi.nlm.nih.gov/pubmed/26057378 http://dx.doi.org/10.1371/journal.pone.0125799 |
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