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Monitoring the Progress towards the Elimination of Gambiense Human African Trypanosomiasis

BACKGROUND: Over the last few years, momentum has gathered around the feasibility and opportunity of eliminating gambiense human African trypanosomiasis (g-HAT). Under the leadership of the World Health Organization (WHO), a large coalition of stakeholders is now committed to achieving this goal. A...

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Autores principales: Simarro, Pere P., Cecchi, Giuliano, Franco, José R., Paone, Massimo, Diarra, Abdoulaye, Priotto, Gerardo, Mattioli, Raffaele C., Jannin, Jean G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461311/
https://www.ncbi.nlm.nih.gov/pubmed/26056823
http://dx.doi.org/10.1371/journal.pntd.0003785
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author Simarro, Pere P.
Cecchi, Giuliano
Franco, José R.
Paone, Massimo
Diarra, Abdoulaye
Priotto, Gerardo
Mattioli, Raffaele C.
Jannin, Jean G.
author_facet Simarro, Pere P.
Cecchi, Giuliano
Franco, José R.
Paone, Massimo
Diarra, Abdoulaye
Priotto, Gerardo
Mattioli, Raffaele C.
Jannin, Jean G.
author_sort Simarro, Pere P.
collection PubMed
description BACKGROUND: Over the last few years, momentum has gathered around the feasibility and opportunity of eliminating gambiense human African trypanosomiasis (g-HAT). Under the leadership of the World Health Organization (WHO), a large coalition of stakeholders is now committed to achieving this goal. A roadmap has been laid out, and indicators and milestones have been defined to monitor the progress of the elimination of g-HAT as a public health problem by 2020. Subsequently, a more ambitious objective was set for 2030: to stop disease transmission. This paper provides a situational update to 2012 for a number of indicators of elimination: number of cases annually reported, geographic distribution of the disease and areas and populations at different levels of risk. RESULTS: Comparing the 5-year periods 2003-2007 and 2008-2012, the area at high or very high risk of g-HAT shrank by 60%, while the area at moderate risk decreased by 22%. These are the areas where g-HAT is still to be considered a public health problem (i.e. > 1 HAT reported case per 10,000 people per annum). This contraction of at-risk areas corresponds to a reduction of 57% for the population at high or very high risk (from 4.1 to 1.8 million), and 20% for moderate risk (from 14.0 to 11.3 million). DISCUSSION: Improved data completeness and accuracy of the Atlas of HAT enhanced our capacity to monitor the progress towards the elimination of g-HAT. The trends in the selected indicators suggest that, in recent years, progress has been steady and in line with the elimination goal laid out in the WHO roadmap on neglected tropical diseases.
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spelling pubmed-44613112015-06-16 Monitoring the Progress towards the Elimination of Gambiense Human African Trypanosomiasis Simarro, Pere P. Cecchi, Giuliano Franco, José R. Paone, Massimo Diarra, Abdoulaye Priotto, Gerardo Mattioli, Raffaele C. Jannin, Jean G. PLoS Negl Trop Dis Research Article BACKGROUND: Over the last few years, momentum has gathered around the feasibility and opportunity of eliminating gambiense human African trypanosomiasis (g-HAT). Under the leadership of the World Health Organization (WHO), a large coalition of stakeholders is now committed to achieving this goal. A roadmap has been laid out, and indicators and milestones have been defined to monitor the progress of the elimination of g-HAT as a public health problem by 2020. Subsequently, a more ambitious objective was set for 2030: to stop disease transmission. This paper provides a situational update to 2012 for a number of indicators of elimination: number of cases annually reported, geographic distribution of the disease and areas and populations at different levels of risk. RESULTS: Comparing the 5-year periods 2003-2007 and 2008-2012, the area at high or very high risk of g-HAT shrank by 60%, while the area at moderate risk decreased by 22%. These are the areas where g-HAT is still to be considered a public health problem (i.e. > 1 HAT reported case per 10,000 people per annum). This contraction of at-risk areas corresponds to a reduction of 57% for the population at high or very high risk (from 4.1 to 1.8 million), and 20% for moderate risk (from 14.0 to 11.3 million). DISCUSSION: Improved data completeness and accuracy of the Atlas of HAT enhanced our capacity to monitor the progress towards the elimination of g-HAT. The trends in the selected indicators suggest that, in recent years, progress has been steady and in line with the elimination goal laid out in the WHO roadmap on neglected tropical diseases. Public Library of Science 2015-06-09 /pmc/articles/PMC4461311/ /pubmed/26056823 http://dx.doi.org/10.1371/journal.pntd.0003785 Text en © 2015 World Health Organization and Food and Agriculture Organization of the United Nations http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Simarro, Pere P.
Cecchi, Giuliano
Franco, José R.
Paone, Massimo
Diarra, Abdoulaye
Priotto, Gerardo
Mattioli, Raffaele C.
Jannin, Jean G.
Monitoring the Progress towards the Elimination of Gambiense Human African Trypanosomiasis
title Monitoring the Progress towards the Elimination of Gambiense Human African Trypanosomiasis
title_full Monitoring the Progress towards the Elimination of Gambiense Human African Trypanosomiasis
title_fullStr Monitoring the Progress towards the Elimination of Gambiense Human African Trypanosomiasis
title_full_unstemmed Monitoring the Progress towards the Elimination of Gambiense Human African Trypanosomiasis
title_short Monitoring the Progress towards the Elimination of Gambiense Human African Trypanosomiasis
title_sort monitoring the progress towards the elimination of gambiense human african trypanosomiasis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461311/
https://www.ncbi.nlm.nih.gov/pubmed/26056823
http://dx.doi.org/10.1371/journal.pntd.0003785
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