HIF-1α Promotes Epithelial-Mesenchymal Transition and Metastasis through Direct Regulation of ZEB1 in Colorectal Cancer

It is well recognized that hypoxia-inducible factor 1 alpha (HIF-1α) is involved in cancer metastasis, chemotherapy and poor prognosis. We previously found that deferoxamine, a hypoxia-mimetic agent, induces epithelial-mesenchymal transition (EMT) in colorectal cancer. Therefore, here we explored a...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Wenjing, Shi, Xinpeng, Peng, Ying, Wu, Meiyan, Zhang, Pei, Xie, Ruyi, Wu, Yao, Yan, Qingqing, Liu, Side, Wang, Jide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461314/
https://www.ncbi.nlm.nih.gov/pubmed/26057751
http://dx.doi.org/10.1371/journal.pone.0129603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461314/
https://www.ncbi.nlm.nih.gov/pubmed/26057751
http://dx.doi.org/10.1371/journal.pone.0129603

Ejemplares similares