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Effect of Ivabradine on Heart Rate and Duration of Exercise in Patients With Mild-to-Moderate Mitral Stenosis: A Randomized Comparison With Metoprolol

BACKGROUND: Symptoms in mitral stenosis (MS) are heart rate (HR) dependent. Increase in HR reduces diastolic filling period with rise in transmitral gradient. By reducing HR, beta-blockers improve hemodynamics and relieve symptoms, but the use may be limited by side effects. The present randomized c...

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Detalles Bibliográficos
Autores principales: Saggu, Daljeet K., Narain, Varun S., Dwivedi, Sudhanshu K., Sethi, Rishi, Chandra, Sharad, Puri, Aniket, Saran, Ram K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461380/
https://www.ncbi.nlm.nih.gov/pubmed/25636072
http://dx.doi.org/10.1097/FJC.0000000000000222