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The Kampo Medicine Yokukansan Decreases MicroRNA-18 Expression and Recovers Glucocorticoid Receptors Protein Expression in the Hypothalamus of Stressed Mice

It is well known that glucocorticoid receptor (GR) signaling regulates the hypothalamic-pituitary-adrenal (HPA) axis, and GR expression level is associated with HPA axis activity. Recent studies revealed that microRNA- (miR-) 18 and/or 124a are candidate negative regulators of GR in the brain. The K...

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Detalles Bibliográficos
Autores principales:	Shimizu, Shoko, Tanaka, Takashi, Takeda, Takashi, Tohyama, Masaya, Miyata, Shingo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461721/ https://www.ncbi.nlm.nih.gov/pubmed/26106615 http://dx.doi.org/10.1155/2015/797280

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