Study on the Dynamic Biological Characteristics of Sca-1(+) Hematopoietic Stem and Progenitor Cell Senescence

The researches in the dynamic changes of the progress of HSCs aging are very limited and necessary. In this study, male C57BL/6 mice were divided into 5 groups by age. We found that the superoxide damage of HSPCs started to increase from the middle age (6 months old), with notably reduced antioxidat...

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Detalles Bibliográficos
Autores principales: Geng, Shan, Mu, Xin-Yi, Chen, Xiong-Bin, Hou, Ji-Ying, Jia, Dao-Yong, Xu, Chun-Yan, Wang, Ya-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461789/
https://www.ncbi.nlm.nih.gov/pubmed/26106432
http://dx.doi.org/10.1155/2015/954120

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