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Familiality and SNP heritability of age at onset and episodicity in major depressive disorder

BACKGROUND: Strategies to dissect phenotypic and genetic heterogeneity of major depressive disorder (MDD) have mainly relied on subphenotypes, such as age at onset (AAO) and recurrence/episodicity. Yet, evidence on whether these subphenotypes are familial or heritable is scarce. The aims of this stu...

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Detalles Bibliográficos
Autores principales: Ferentinos, P., Koukounari, A., Power, R., Rivera, M., Uher, R., Craddock, N., Owen, M. J., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Ising, M., Maier, W., Mors, O., Rietschel, M., Preisig, M., Binder, E. B., Aitchison, K. J., Mendlewicz, J., Souery, D., Hauser, J., Henigsberg, N., Breen, G., Craig, I. W., Farmer, A. E., Müller-Myhsok, B., McGuffin, P., Lewis, C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462162/
https://www.ncbi.nlm.nih.gov/pubmed/25698070
http://dx.doi.org/10.1017/S0033291715000215