Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models

Eribulin mesylate is a synthetic macrocyclic ketone analog of the marine sponge natural product halichondrin B and an inhibitor of microtubule dynamics. Some tubulin-binding drugs are known to have antivascular (antiangiogenesis or vascular-disrupting) activities that can target abnormal tumor vesse...

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Detalles Bibliográficos
Autores principales: Funahashi, Yasuhiro, Okamoto, Kiyoshi, Adachi, Yusuke, Semba, Taro, Uesugi, Mai, Ozawa, Yoichi, Tohyama, Osamu, Uehara, Taisuke, Kimura, Takayuki, Watanabe, Hideki, Asano, Makoto, Kawano, Satoshi, Tizon, Xavier, McCracken, Paul J, Matsui, Junji, Aoshima, Ken, Nomoto, Kenichi, Oda, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462349/
https://www.ncbi.nlm.nih.gov/pubmed/25060424
http://dx.doi.org/10.1111/cas.12488

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