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BRCA1 promoter methylation of normal breast epithelial cells as a possible precursor for BRCA1-methylated breast cancer

The breast cancer susceptibility gene 1 (BRCA1) and glutathione S-transferase P1 (GSTP1) promoters are reportedly often methylated in breast cancer tissues. Their methylation status in surrounding normal breast tissues has not been examined thoroughly although this may well be important for a better...

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Detalles Bibliográficos
Autores principales: Otani, Yoko, Miyake, Tomohiro, Kagara, Naofumi, Shimoda, Masafumi, Naoi, Yasuto, Maruyama, Naomi, Shimomura, Atsuhi, Shimazu, Kenzo, Kim, Seung Jin, Noguchi, Shinzaburo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462354/
https://www.ncbi.nlm.nih.gov/pubmed/25155055
http://dx.doi.org/10.1111/cas.12506