Epigenetic modifications of splicing factor genes in myelodysplastic syndromes and acute myeloid leukemia

Somatic mutations in splicing factor genes have frequently been reported in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Although aberrant epigenetic changes are frequently implicated in blood cancers, their direct role in suppressing one or both alleles of critical splicing fac...

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Detalles Bibliográficos
Autores principales: Wong, Justin J-L, Lau, Katherine A, Pinello, Natalia, Rasko, John E J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462368/
https://www.ncbi.nlm.nih.gov/pubmed/25220401
http://dx.doi.org/10.1111/cas.12532

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