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DEGS2 polymorphism associated with cognition in schizophrenia is associated with gene expression in brain
A genome-wide association study of cognitive deficits in patients with schizophrenia in Japan found association with a missense genetic variant (rs7157599, Asn8Ser) in the delta(4)-desaturase, sphingolipid 2 (DEGS2) gene. A replication analysis using Caucasian samples showed a directionally consiste...
Autores principales: | Ohi, K, Ursini, G, Li, M, Shin, J H, Ye, T, Chen, Q, Tao, R, Kleinman, J E, Hyde, T M, Hashimoto, R, Weinberger, D R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462608/ https://www.ncbi.nlm.nih.gov/pubmed/25871975 http://dx.doi.org/10.1038/tp.2015.45 |
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