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Caffeine increases striatal dopamine D(2)/D(3) receptor availability in the human brain
Caffeine, the most widely consumed psychoactive substance in the world, is used to promote wakefulness and enhance alertness. Like other wake-promoting drugs (stimulants and modafinil), caffeine enhances dopamine (DA) signaling in the brain, which it does predominantly by antagonizing adenosine A(2A...
Autores principales: | Volkow, N D, Wang, G-J, Logan, J, Alexoff, D, Fowler, J S, Thanos, P K, Wong, C, Casado, V, Ferre, S, Tomasi, D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462609/ https://www.ncbi.nlm.nih.gov/pubmed/25871974 http://dx.doi.org/10.1038/tp.2015.46 |
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