Kaposi Sarcoma Herpesvirus Induces HO-1 during De Novo Infection of Endothelial Cells via Viral miRNA-Dependent and -Independent Mechanisms

Kaposi sarcoma (KS) herpesvirus (KSHV) infection of endothelial cells (EC) is associated with strong induction of heme oxygenase-1 (HO-1), a stress-inducible host gene that encodes the rate-limiting enzyme responsible for heme catabolism. KS is an angioproliferative tumor characterized by the prolif...

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Detalles Bibliográficos
Autores principales: Botto, Sara, Totonchy, Jennifer E., Gustin, Jean K., Moses, Ashlee V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462627/
https://www.ncbi.nlm.nih.gov/pubmed/26045540
http://dx.doi.org/10.1128/mBio.00668-15

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