HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity

Intestinal epithelial cells (IECs) are exposed to profound fluctuations in oxygen tension and have evolved adaptive transcriptional responses to a low-oxygen environment. These adaptations are mediated primarily through the hypoxia-inducible factor (HIF) complex. Given the central role of the IEC in...

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Detalles Bibliográficos
Autores principales: Saeedi, Bejan J., Kao, Daniel J., Kitzenberg, David A., Dobrinskikh, Evgenia, Schwisow, Kayla D., Masterson, Joanne C., Kendrick, Agnieszka A., Kelly, Caleb J., Bayless, Amanda J., Kominsky, Douglas J., Campbell, Eric L., Kuhn, Kristine A., Furuta, Glenn T., Colgan, Sean P., Glover, Louise E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462943/
https://www.ncbi.nlm.nih.gov/pubmed/25904334
http://dx.doi.org/10.1091/mbc.E14-07-1194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462943/
https://www.ncbi.nlm.nih.gov/pubmed/25904334
http://dx.doi.org/10.1091/mbc.E14-07-1194

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