Detection of T-Cadherin Expression in Mouse Embryos

The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the develo...

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Detalles Bibliográficos
Autores principales: Rubina, K. A., Smutova, V. A., Semenova, M. L., Poliakov, A. A., Gerety, S., Wilkinson, D., Surkova, E. I., Semina, E. V., Sysoeva, V. Yu., Tkachuk, V. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463417/
https://www.ncbi.nlm.nih.gov/pubmed/26085949
Descripción
Sumario:The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the developing brain, starting with the E8.75 stage, and in the heart, starting with the E11.5 stage. These data suggest a possible involvement of T-cadherin in the formation of blood vessels during embryogenesis.

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