Detection of T-Cadherin Expression in Mouse Embryos

The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the develo...

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Autores principales: Rubina, K. A., Smutova, V. A., Semenova, M. L., Poliakov, A. A., Gerety, S., Wilkinson, D., Surkova, E. I., Semina, E. V., Sysoeva, V. Yu., Tkachuk, V. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463417/
https://www.ncbi.nlm.nih.gov/pubmed/26085949
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author Rubina, K. A.
Smutova, V. A.
Semenova, M. L.
Poliakov, A. A.
Gerety, S.
Wilkinson, D.
Surkova, E. I.
Semina, E. V.
Sysoeva, V. Yu.
Tkachuk, V. A.
author_facet Rubina, K. A.
Smutova, V. A.
Semenova, M. L.
Poliakov, A. A.
Gerety, S.
Wilkinson, D.
Surkova, E. I.
Semina, E. V.
Sysoeva, V. Yu.
Tkachuk, V. A.
author_sort Rubina, K. A.
collection PubMed
description The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the developing brain, starting with the E8.75 stage, and in the heart, starting with the E11.5 stage. These data suggest a possible involvement of T-cadherin in the formation of blood vessels during embryogenesis.
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spelling pubmed-44634172015-06-17 Detection of T-Cadherin Expression in Mouse Embryos Rubina, K. A. Smutova, V. A. Semenova, M. L. Poliakov, A. A. Gerety, S. Wilkinson, D. Surkova, E. I. Semina, E. V. Sysoeva, V. Yu. Tkachuk, V. A. Acta Naturae Research Article The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the developing brain, starting with the E8.75 stage, and in the heart, starting with the E11.5 stage. These data suggest a possible involvement of T-cadherin in the formation of blood vessels during embryogenesis. A.I. Gordeyev 2015 /pmc/articles/PMC4463417/ /pubmed/26085949 Text en Copyright ® 2015 Park-media Ltd. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Rubina, K. A.
Smutova, V. A.
Semenova, M. L.
Poliakov, A. A.
Gerety, S.
Wilkinson, D.
Surkova, E. I.
Semina, E. V.
Sysoeva, V. Yu.
Tkachuk, V. A.
Detection of T-Cadherin Expression in Mouse Embryos
title Detection of T-Cadherin Expression in Mouse Embryos
title_full Detection of T-Cadherin Expression in Mouse Embryos
title_fullStr Detection of T-Cadherin Expression in Mouse Embryos
title_full_unstemmed Detection of T-Cadherin Expression in Mouse Embryos
title_short Detection of T-Cadherin Expression in Mouse Embryos
title_sort detection of t-cadherin expression in mouse embryos
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463417/
https://www.ncbi.nlm.nih.gov/pubmed/26085949
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