Risk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening

PURPOSE: Cancer screening strategies have commonly adopted single-biomarker thresholds to identify abnormality. We investigated the impact of serial biomarker change interpreted through a risk algorithm on cancer detection rates. PATIENTS AND METHODS: In the United Kingdom Collaborative Trial of Ova...

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Detalles Bibliográficos
Autores principales: Menon, Usha, Ryan, Andy, Kalsi, Jatinderpal, Gentry-Maharaj, Aleksandra, Dawnay, Anne, Habib, Mariam, Apostolidou, Sophia, Singh, Naveena, Benjamin, Elizabeth, Burnell, Matthew, Davies, Susan, Sharma, Aarti, Gunu, Richard, Godfrey, Keith, Lopes, Alberto, Oram, David, Herod, Jonathan, Williamson, Karin, Seif, Mourad W., Jenkins, Howard, Mould, Tim, Woolas, Robert, Murdoch, John B., Dobbs, Stephen, Amso, Nazar N., Leeson, Simon, Cruickshank, Derek, Scott, Ian, Fallowfield, Lesley, Widschwendter, Martin, Reynolds, Karina, McGuire, Alistair, Campbell, Stuart, Parmar, Mahesh, Skates, Steven J., Jacobs, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2015
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463475/
https://www.ncbi.nlm.nih.gov/pubmed/25964255
http://dx.doi.org/10.1200/JCO.2014.59.4945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463475/
https://www.ncbi.nlm.nih.gov/pubmed/25964255
http://dx.doi.org/10.1200/JCO.2014.59.4945

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