Genomic Analysis of Broad-Host-Range Enterobacteriophage Av-05

Lytic bacteriophages have reemerged as an alternative for the control of pathogenic bacteria. However, the effective use of phage relies on appropriate genomic characterization. In this study, we report the genome of bacteriophage Av-05 and its sequence analysis, which has strong lytic activity agai...

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Autores principales: Amarillas, Luis, López-Cuevas, Osvaldo, León-Félix, Josefina, Castro-del Campo, Nohelia, Gerba, Charles P., Chaidez, Cristóbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Viruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463512/
https://www.ncbi.nlm.nih.gov/pubmed/26067947
http://dx.doi.org/10.1128/genomeA.00282-15
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author Amarillas, Luis
López-Cuevas, Osvaldo
León-Félix, Josefina
Castro-del Campo, Nohelia
Gerba, Charles P.
Chaidez, Cristóbal
author_facet Amarillas, Luis
López-Cuevas, Osvaldo
León-Félix, Josefina
Castro-del Campo, Nohelia
Gerba, Charles P.
Chaidez, Cristóbal
author_sort Amarillas, Luis
collection PubMed
description Lytic bacteriophages have reemerged as an alternative for the control of pathogenic bacteria. However, the effective use of phage relies on appropriate genomic characterization. In this study, we report the genome of bacteriophage Av-05 and its sequence analysis, which has strong lytic activity against Escherichia coli O157:H7 strains and several Salmonella serotypes. The analysis revealed that the phage Av-05 genome consists of 120,938 bp, containing 209 putative open reading frames (ORFs) and 9 tRNAs.
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spelling pubmed-44635122015-06-18 Genomic Analysis of Broad-Host-Range Enterobacteriophage Av-05 Amarillas, Luis López-Cuevas, Osvaldo León-Félix, Josefina Castro-del Campo, Nohelia Gerba, Charles P. Chaidez, Cristóbal Genome Announc Viruses Lytic bacteriophages have reemerged as an alternative for the control of pathogenic bacteria. However, the effective use of phage relies on appropriate genomic characterization. In this study, we report the genome of bacteriophage Av-05 and its sequence analysis, which has strong lytic activity against Escherichia coli O157:H7 strains and several Salmonella serotypes. The analysis revealed that the phage Av-05 genome consists of 120,938 bp, containing 209 putative open reading frames (ORFs) and 9 tRNAs. American Society for Microbiology 2015-06-11 /pmc/articles/PMC4463512/ /pubmed/26067947 http://dx.doi.org/10.1128/genomeA.00282-15 Text en Copyright © 2015 Amarillas et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Viruses
Amarillas, Luis
López-Cuevas, Osvaldo
León-Félix, Josefina
Castro-del Campo, Nohelia
Gerba, Charles P.
Chaidez, Cristóbal
Genomic Analysis of Broad-Host-Range Enterobacteriophage Av-05
title Genomic Analysis of Broad-Host-Range Enterobacteriophage Av-05
title_full Genomic Analysis of Broad-Host-Range Enterobacteriophage Av-05
title_fullStr Genomic Analysis of Broad-Host-Range Enterobacteriophage Av-05
title_full_unstemmed Genomic Analysis of Broad-Host-Range Enterobacteriophage Av-05
title_short Genomic Analysis of Broad-Host-Range Enterobacteriophage Av-05
title_sort genomic analysis of broad-host-range enterobacteriophage av-05
topic Viruses
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463512/
https://www.ncbi.nlm.nih.gov/pubmed/26067947
http://dx.doi.org/10.1128/genomeA.00282-15
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