Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210

To assess the genetic factors contributing to daptomycin resistance in Staphylococcus aureus, the draft genome of a clinically derived daptomycin-nonsusceptible isolate APS211 was generated and compared to the draft sequence of its susceptible progenitor strain APS210. Four genetic differences were...

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Detalles Bibliográficos
Autores principales: Cameron, David R., Jiang, Jhih-Hang, Abbott, Iain J., Spelman, Denis W., Peleg, Anton Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463516/
https://www.ncbi.nlm.nih.gov/pubmed/26067951
http://dx.doi.org/10.1128/genomeA.00568-15
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author Cameron, David R.
Jiang, Jhih-Hang
Abbott, Iain J.
Spelman, Denis W.
Peleg, Anton Y.
author_facet Cameron, David R.
Jiang, Jhih-Hang
Abbott, Iain J.
Spelman, Denis W.
Peleg, Anton Y.
author_sort Cameron, David R.
collection PubMed
description To assess the genetic factors contributing to daptomycin resistance in Staphylococcus aureus, the draft genome of a clinically derived daptomycin-nonsusceptible isolate APS211 was generated and compared to the draft sequence of its susceptible progenitor strain APS210. Four genetic differences were identified including a previously described mutation within the mprF gene.
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spelling pubmed-44635162015-06-18 Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210 Cameron, David R. Jiang, Jhih-Hang Abbott, Iain J. Spelman, Denis W. Peleg, Anton Y. Genome Announc Prokaryotes To assess the genetic factors contributing to daptomycin resistance in Staphylococcus aureus, the draft genome of a clinically derived daptomycin-nonsusceptible isolate APS211 was generated and compared to the draft sequence of its susceptible progenitor strain APS210. Four genetic differences were identified including a previously described mutation within the mprF gene. American Society for Microbiology 2015-06-11 /pmc/articles/PMC4463516/ /pubmed/26067951 http://dx.doi.org/10.1128/genomeA.00568-15 Text en Copyright © 2015 Cameron et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Prokaryotes
Cameron, David R.
Jiang, Jhih-Hang
Abbott, Iain J.
Spelman, Denis W.
Peleg, Anton Y.
Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210
title Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210
title_full Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210
title_fullStr Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210
title_full_unstemmed Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210
title_short Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210
title_sort draft genome sequences of clinical daptomycin-nonsusceptible methicillin-resistant staphylococcus aureus strain aps211 and its daptomycin-susceptible progenitor aps210
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463516/
https://www.ncbi.nlm.nih.gov/pubmed/26067951
http://dx.doi.org/10.1128/genomeA.00568-15
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