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Nucleotide Salvage Deficiencies, DNA Damage and Neurodegeneration

Nucleotide balance is critically important not only in replicating cells but also in quiescent cells. This is especially true in the nervous system, where there is a high demand for adenosine triphosphate (ATP) produced from mitochondria. Mitochondria are particularly prone to oxidative stress-assoc...

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Detalles Bibliográficos
Autores principales: Fasullo, Michael, Endres, Lauren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463597/
https://www.ncbi.nlm.nih.gov/pubmed/25923076
http://dx.doi.org/10.3390/ijms16059431