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Nucleotide Salvage Deficiencies, DNA Damage and Neurodegeneration
Nucleotide balance is critically important not only in replicating cells but also in quiescent cells. This is especially true in the nervous system, where there is a high demand for adenosine triphosphate (ATP) produced from mitochondria. Mitochondria are particularly prone to oxidative stress-assoc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463597/ https://www.ncbi.nlm.nih.gov/pubmed/25923076 http://dx.doi.org/10.3390/ijms16059431 |