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Structural Basis for Carbapenem-Hydrolyzing Mechanisms of Carbapenemases Conferring Antibiotic Resistance
Carbapenems (imipenem, meropenem, biapenem, ertapenem, and doripenem) are β-lactam antimicrobial agents. Because carbapenems have the broadest spectra among all β-lactams and are primarily used to treat infections by multi-resistant Gram-negative bacteria, the emergence and spread of carbapenemases...
Autores principales: | Jeon, Jeong Ho, Lee, Jung Hun, Lee, Jae Jin, Park, Kwang Seung, Karim, Asad Mustafa, Lee, Chang-Ro, Jeong, Byeong Chul, Lee, Sang Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463611/ https://www.ncbi.nlm.nih.gov/pubmed/25938965 http://dx.doi.org/10.3390/ijms16059654 |
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