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Cell Adhesion and in Vivo Osseointegration of Sandblasted/Acid Etched/Anodized Dental Implants

The authors describe a new type of titanium (Ti) implant as a Modi-anodized (ANO) Ti implant, the surface of which was treated by sandblasting, acid etching (SLA), and anodized techniques. The aim of the present study was to evaluate the adhesion of MG-63 cells to Modi-ANO surface treated Ti in vitr...

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Autores principales: Kim, Mu-Hyon, Park, Kyeongsoon, Choi, Kyung-Hee, Kim, Soo-Hong, Kim, Se Eun, Jeong, Chang-Mo, Huh, Jung-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463648/
https://www.ncbi.nlm.nih.gov/pubmed/25955650
http://dx.doi.org/10.3390/ijms160510324
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author Kim, Mu-Hyon
Park, Kyeongsoon
Choi, Kyung-Hee
Kim, Soo-Hong
Kim, Se Eun
Jeong, Chang-Mo
Huh, Jung-Bo
author_facet Kim, Mu-Hyon
Park, Kyeongsoon
Choi, Kyung-Hee
Kim, Soo-Hong
Kim, Se Eun
Jeong, Chang-Mo
Huh, Jung-Bo
author_sort Kim, Mu-Hyon
collection PubMed
description The authors describe a new type of titanium (Ti) implant as a Modi-anodized (ANO) Ti implant, the surface of which was treated by sandblasting, acid etching (SLA), and anodized techniques. The aim of the present study was to evaluate the adhesion of MG-63 cells to Modi-ANO surface treated Ti in vitro and to investigate its osseointegration characteristics in vivo. Four different types of Ti implants were examined, that is, machined Ti (control), SLA, anodized, and Modi-ANO Ti. In the cell adhesion study, Modi-ANO Ti showed higher initial MG-63 cell adhesion and induced greater filopodia growth than other groups. In vivo study in a beagle model revealed the bone-to-implant contact (BIC) of Modi-ANO Ti (74.20% ± 10.89%) was much greater than those of machined (33.58% ± 8.63%), SLA (58.47% ± 12.89), or ANO Ti (59.62% ± 18.30%). In conclusion, this study demonstrates that Modi-ANO Ti implants produced by sandblasting, acid etching, and anodizing improve cell adhesion and bone ongrowth as compared with machined, SLA, or ANO Ti implants. These findings suggest that the application of Modi-ANO surface treatment could improve the osseointegration of dental implant.
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spelling pubmed-44636482015-06-16 Cell Adhesion and in Vivo Osseointegration of Sandblasted/Acid Etched/Anodized Dental Implants Kim, Mu-Hyon Park, Kyeongsoon Choi, Kyung-Hee Kim, Soo-Hong Kim, Se Eun Jeong, Chang-Mo Huh, Jung-Bo Int J Mol Sci Article The authors describe a new type of titanium (Ti) implant as a Modi-anodized (ANO) Ti implant, the surface of which was treated by sandblasting, acid etching (SLA), and anodized techniques. The aim of the present study was to evaluate the adhesion of MG-63 cells to Modi-ANO surface treated Ti in vitro and to investigate its osseointegration characteristics in vivo. Four different types of Ti implants were examined, that is, machined Ti (control), SLA, anodized, and Modi-ANO Ti. In the cell adhesion study, Modi-ANO Ti showed higher initial MG-63 cell adhesion and induced greater filopodia growth than other groups. In vivo study in a beagle model revealed the bone-to-implant contact (BIC) of Modi-ANO Ti (74.20% ± 10.89%) was much greater than those of machined (33.58% ± 8.63%), SLA (58.47% ± 12.89), or ANO Ti (59.62% ± 18.30%). In conclusion, this study demonstrates that Modi-ANO Ti implants produced by sandblasting, acid etching, and anodizing improve cell adhesion and bone ongrowth as compared with machined, SLA, or ANO Ti implants. These findings suggest that the application of Modi-ANO surface treatment could improve the osseointegration of dental implant. MDPI 2015-05-06 /pmc/articles/PMC4463648/ /pubmed/25955650 http://dx.doi.org/10.3390/ijms160510324 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kim, Mu-Hyon
Park, Kyeongsoon
Choi, Kyung-Hee
Kim, Soo-Hong
Kim, Se Eun
Jeong, Chang-Mo
Huh, Jung-Bo
Cell Adhesion and in Vivo Osseointegration of Sandblasted/Acid Etched/Anodized Dental Implants
title Cell Adhesion and in Vivo Osseointegration of Sandblasted/Acid Etched/Anodized Dental Implants
title_full Cell Adhesion and in Vivo Osseointegration of Sandblasted/Acid Etched/Anodized Dental Implants
title_fullStr Cell Adhesion and in Vivo Osseointegration of Sandblasted/Acid Etched/Anodized Dental Implants
title_full_unstemmed Cell Adhesion and in Vivo Osseointegration of Sandblasted/Acid Etched/Anodized Dental Implants
title_short Cell Adhesion and in Vivo Osseointegration of Sandblasted/Acid Etched/Anodized Dental Implants
title_sort cell adhesion and in vivo osseointegration of sandblasted/acid etched/anodized dental implants
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463648/
https://www.ncbi.nlm.nih.gov/pubmed/25955650
http://dx.doi.org/10.3390/ijms160510324
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