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Optimal Decision Rules for Biomarker-Based Subgroup Selection for a Targeted Therapy in Oncology
Throughout recent years, there has been a rapidly increasing interest regarding the evaluation of so-called targeted therapies. These therapies are assumed to show a greater benefit in a pre-specified subgroup of patients—commonly identified by a predictive biomarker—as compared to the total patient...
Autores principales: | Krisam, Johannes, Kieser, Meinhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463650/ https://www.ncbi.nlm.nih.gov/pubmed/25961947 http://dx.doi.org/10.3390/ijms160510354 |
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