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Optimal Decision Rules for Biomarker-Based Subgroup Selection for a Targeted Therapy in Oncology

Throughout recent years, there has been a rapidly increasing interest regarding the evaluation of so-called targeted therapies. These therapies are assumed to show a greater benefit in a pre-specified subgroup of patients—commonly identified by a predictive biomarker—as compared to the total patient...

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Detalles Bibliográficos
Autores principales: Krisam, Johannes, Kieser, Meinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463650/
https://www.ncbi.nlm.nih.gov/pubmed/25961947
http://dx.doi.org/10.3390/ijms160510354

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