Serum Amyloid A Receptor Blockade and Incorporation into High-Density Lipoprotein Modulates Its Pro-Inflammatory and Pro-Thrombotic Activities on Vascular Endothelial Cells

The acute phase protein serum amyloid A (SAA), a marker of inflammation, induces expression of pro-inflammatory and pro-thrombotic mediators including ICAM-1, VCAM-1, IL-6, IL-8, MCP-1 and tissue factor (TF) in both monocytes/macrophages and endothelial cells, and induces endothelial dysfunction—a p...

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Detalles Bibliográficos
Autores principales: Chami, Belal, Barrie, Nicola, Cai, Xiaoping, Wang, Xiaosuo, Paul, Moumita, Morton-Chandra, Rebecca, Sharland, Alexandra, Dennis, Joanne M., Freedman, Saul B., Witting, Paul K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463692/
https://www.ncbi.nlm.nih.gov/pubmed/25988387
http://dx.doi.org/10.3390/ijms160511101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463692/
https://www.ncbi.nlm.nih.gov/pubmed/25988387
http://dx.doi.org/10.3390/ijms160511101

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