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A cost-effective and efficient reprogramming platform for large-scale production of integration-free human induced pluripotent stem cells in chemically defined culture
Factors limiting the adoption of iPSC technology include the cost of developing lines and the time period that it takes to characterize and bank them, particularly when integration free, feeder free, and Xeno-free components are used. In this manuscript we describe our optimization procedure that en...
Autores principales: | Beers, Jeanette, Linask, Kaari L., Chen, Jane A., Siniscalchi, Lauren I., Lin, Yongshun, Zheng, Wei, Rao, Mahendra, Chen, Guokai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464084/ https://www.ncbi.nlm.nih.gov/pubmed/26066579 http://dx.doi.org/10.1038/srep11319 |
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