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Kissing loop interaction in adenine riboswitch: insights from umbrella sampling simulations

INTRODUCTION: Riboswitches are cis-acting regulatory RNA elements prevalently located in the leader sequences of bacterial mRNA. An adenine sensing riboswitch cis-regulates adeninosine deaminase gene (add) in Vibrio vulnificus. The structural mechanism regulating its conformational changes upon liga...

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Detalles Bibliográficos
Autores principales:	Di Palma, Francesco, Bottaro, Sandro, Bussi, Giovanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464220/ https://www.ncbi.nlm.nih.gov/pubmed/26051557 http://dx.doi.org/10.1186/1471-2105-16-S9-S6

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