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Osteopontin mediates survival, proliferation and migration of neural stem cells through the chemokine receptor CXCR4
INTRODUCTION: Osteopontin (OPN) is a phosphoglycoprotein with important roles in tissue homeostasis, wound healing, immune regulation, and stress responses. It is expressed constitutively in the brain and upregulated during neuroinflammatory responses; for example, after focal cerebral ischemia. To...
Autores principales: | Rabenstein, Monika, Hucklenbroich, Joerg, Willuweit, Antje, Ladwig, Anne, Fink, Gereon Rudolf, Schroeter, Michael, Langen, Karl-Josef, Rueger, Maria Adele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464234/ https://www.ncbi.nlm.nih.gov/pubmed/25998490 http://dx.doi.org/10.1186/s13287-015-0098-x |
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