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Tumor-induced loss of mural Connexin 43 gap junction activity promotes endothelial proliferation

BACKGROUND: Proper functional association between mural cells and endothelial cells (EC) causes EC of blood vessels to become quiescent. Mural cells on tumor vessels exhibit decreased attachment to EC, which allows vessels to be unstable and proliferative. The mechanisms by which tumors prevent prop...

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Detalles Bibliográficos
Autores principales:	Choudhary, Mayur, Naczki, Christine, Chen, Wenhong, Barlow, Keith D., Case, L. Douglas, Metheny-Barlow, Linda J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464240/ https://www.ncbi.nlm.nih.gov/pubmed/26002762 http://dx.doi.org/10.1186/s12885-015-1420-9

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