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Caveolin-1 is Associated with Tumor Progression and Confers a Multi-Modality Resistance Phenotype in Pancreatic Cancer
Caveolin-1 (Cav-1) is a 21 kDa protein enriched in caveolae, and has been implicated in oncogenic cell transformation, tumorigenesis, and metastasis. We explored roles for Cav-1 in pancreatic cancer (PC) prognostication, tumor progression, resistance to therapy, and whether targeted downregulation c...
Autores principales: | Chatterjee, Moumita, Ben-Josef, Edgar, Thomas, Dafydd G., Morgan, Meredith A., Zalupski, Mark M., Khan, Gazala, Andrew Robinson, Charles, Griffith, Kent A., Chen, Ching-Shih, Ludwig, Thomas, Bekaii-Saab, Tanios, Chakravarti, Arnab, Williams, Terence M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464260/ https://www.ncbi.nlm.nih.gov/pubmed/26065715 http://dx.doi.org/10.1038/srep10867 |
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