Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model?

The EU FP6 project carcinoGENOMICS explored the combination of toxicogenomics and in vitro cell culture models for identifying organotypical genotoxic- and non-genotoxic carcinogen-specific gene signatures. Here the performance of its gene classifier, derived from exposure of metabolically competent...

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Detalles Bibliográficos
Autores principales: Doktorova, T. Y., Yildirimman, Reha, Ceelen, Liesbeth, Vilardell, Mireia, Vanhaecke, Tamara, Vinken, Mathieu, Ates, Gamze, Heymans, Anja, Gmuender, Hans, Bort, Roque, Corvi, Raffaella, Phrakonkham, Pascal, Li, Ruoya, Mouchet, Nicolas, Chesne, Christophe, van Delft, Joost, Kleinjans, Jos, Castell, Jose, Herwig, Ralf, Rogiers, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464292/
https://www.ncbi.nlm.nih.gov/pubmed/26417288

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